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Article

Transcription factor AP‐2γ, a novel marker of gonocytes and seminomatous germ cell tumors

7 Feb 2005

Abstract excerpt

Most germ cell tumors (GCTs) arise from intratubular germ cell neoplasias (IGCNUs, also referred to as carcinoma in situ), which are thought to originate from a transformed fetal germ cell, the gonocyte. However, the nature of the molecular pathways involved in IGCNU formation remains elusive. Therefore, identification of novel oncofetal markers is an important prerequisite to further our understanding of the...

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PMID: 15700319
DOI: 10.1002/ijc.20913

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