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Article

Stem cell factor as a novel diagnostic marker for early malignant germ cells

6 May 2008

Abstract excerpt

Carcinoma in situ (CIS) of the testis is the pre-invasive stage of type II testicular germ cell tumours (TGCTs) of adolescents and adults. These tumours are the most frequently diagnosed cancer in Caucasian adolescents and young adults. In dysgenetic gonads, the precursor of type II GCTs can be either CIS or a lesion known as gonadoblastoma (GB). CIS/GB originates from a primordial germ cell (PGC)/gonocyte, ie an...

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PMID: 18566970
DOI: 10.1002/path.2378

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