Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of BLIMP1/PRMT5and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumors

7 Nov 2008

Abstract excerpt

BACKGROUND: Most testicular germ cell tumors arise from intratubular germ cell neoplasia unclassified (IGCNU, also referred to as carcinoma in situ), which is thought to originate from a transformed primordial germ cell (PGC)/gonocyte, the fetal germ cell. Analyses of the molecular profile of IGCNU and seminoma show similarities to the expression profile of fetal germ cells/gonocytes. In murine PGCs, expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Epigenetics and DNA Methylation
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 18992153
DOI: 10.1186/1471-213x-8-106

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of BLIMP1/PRMT5and concurrent histone H2A/H4 arginine 3 dimethylation in fetal germ cells, CIS/IGCNU and germ cell tumorsPMID 18992153Read ↗

Genome Wide DNA Methylation Profiles Provide Clues to the Origin and Pathogenesis of Germ Cell TumorsSemantic proximity Read ↗

Epigenetics and Testicular Cancer: Bridging the Gap Between Fundamental Biology and Patient CareSemantic proximity Read ↗

Seminoma and Embryonal Carcinoma Footprints Identified by Analysis of Integrated Genome-Wide Epigenetic and Expression Profiles of Germ Cell Cancer Cell LinesSemantic proximity Read ↗

Immunohistochemical Profiling of Germ Cells Within the Human Fetal Testis: Identification of Three SubpopulationsSemantic proximity Read ↗

PRDM14 is expressed in germ cell tumors with constitutive overexpression altering human germline differentiation and proliferationSemantic proximity Read ↗

Multipoint imprinting analysis indicates a common precursor cell for gonadal and nongonadal pediatric germ cell tumors.Semantic proximity Read ↗

The Sm protein methyltransferase PRMT5 is not required for primordial germ cell specification in mice.Semantic proximity Read ↗

Molecular and epigenetic pathogenesis of germ cell tumorsSemantic proximity Read ↗

Carcinoma in situ testis displays permissive chromatin modifications similar to immature foetal germ cellsSemantic proximity Read ↗

Specification of the germ cell lineage in mice: A process orchestrated by the PR-domain proteins, Blimp1 and Prdm14Semantic proximity Read ↗

Cripto: Expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumorsSemantic proximity Read ↗

Epigenetic reprogramming in mouse primordial germ cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.