Article
Mutations that eliminate the requirement for the vertex protein in bacteriophage T4 capsid assembly.
Journal of molecular biology - 5 Apr 1992
Johnson K, Condie B, Mooney D T, Doermann A H
Abstract excerpt
The capsid of bacteriophage T4 is composed of two essential structural proteins, gp23, the major constituent of the capsid, and gp24, a less prevalent protein that is located in the pentameric vertices of the capsid. gp24 is required both to stabilize the capsid and to allow it to be further matured. This requirement can be eliminated by bypass-24 (byp24) mutations within g23. We have isolated, cloned and...
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