Article
Novel mutants in the 5' upstream region of the portal protein gene 20 overcome a gp40-dependent prohead assembly block in bacteriophage T4.
Journal of molecular biology - 8 Nov 1996
Yap N L, Rao V B
Abstract excerpt
The exact mechanism by which the double-stranded (ds) DNA bacteriophages incorporate the portal protein at a unique vertex of the icosahedral capsid is unknown. In phage T4, there is evidence that this vertex, constituted by 12 subunits of gp20, acts as an initiator for the assembly of the major...
Topics
- Bacteriophage T4
- Base Sequence
- Capsid
- Capsid Proteins
- Gene Expression Regulation, Viral
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Phenotype
- Point Mutation
- RNA, Viral
- Transcription, Genetic
- Viral Nonstructural Proteins