Article
Novel second-site suppression of a cold-sensitive defect in phage P22 procapsid assembly.
Journal of molecular biology - 5 Dec 1990
Bazinet C, Villafane R, King J
Abstract excerpt
The DNA packaging portal of the phage P22 procapsid is formed of 12 molecules of the 90,000 dalton gene 1 protein. The assembly of this dodecameric complex at a unique capsid vertex requires scaffolding subunits. The mechanism that ensures the location of the 12-fold symmetrical portal at only one of the 12 5-fold vertices of an icosahedral virus capsid presents a unique assembly problem, which, in some viruses,...
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