Article
Systematic repeat addition at a precise location in the coding region of the involucrin gene of wild mice reveals their phylogeny.
Genetics - 1 Apr 2005
Djian Philippe, Delhomme Brigitte
Abstract excerpt
The involucrin gene encodes a protein of terminally differentiated keratinocytes. Its segment of repeats, which represents up to 80% of the coding region, is highly polymorphic in mouse strains derived from wild progenitors. Polymorphism includes nucleotide substitutions, but is most strikingly due to the recent addition of a variable number of repeats at a precise location within the segment of repeats. Each...
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