Article
ACE insert/delete polymorphism and atherosclerosis.
Atherosclerosis - 1 Feb 2005
Scheer W Douglas, Boudreau Donald A, Hixson James E, McGill Henry C, Newman William P, Tracy Richard E, Zieske Arthur W, Strong Jack P
Abstract excerpt
We report on the results of a large autopsy study focusing upon the hypothesis that deletion of the Alu insert in the angiotensin converting enzyme (ACE) gene is associated with: (a) greater prevalence or extent of atherosclerosis in the aorta and coronary arteries; and (b) microscopic qualities of established atherosclerotic plaques in the coronary arteries. This study was conducted in young US black (n=290) and...
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