Article
Apolipoprotein E polymorphisms affect atherosclerosis in young males. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group.
Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jan 2000
Hixson J E
Abstract excerpt
Investigators in eight communities collected aortas, right coronary arteries, blood and liver samples, and associated information from 720 young males, aged 15-34 years, who died of external causes. Genotypes for apolipoprotein (apo) E isoforms (E2, E3, and E4) were determined from hepatic DNA by restriction isotyping (restriction enzyme isoform genotyping) of amplified apo E sequences. Pathologists graded the...
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