Apolipoprotein E polymorphisms affect atherosclerosis in young males. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group.

doi:10.1161/01.atv.11.5.1237

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Article

Apolipoprotein E polymorphisms affect atherosclerosis in young males. Pathobiological Determinants of Atherosclerosis in Youth (PDAY) Research Group.

Arteriosclerosis and thrombosis : a journal of vascular biology - 1 Jan 2000

Hixson J E

Abstract excerpt

Investigators in eight communities collected aortas, right coronary arteries, blood and liver samples, and associated information from 720 young males, aged 15-34 years, who died of external causes. Genotypes for apolipoprotein (apo) E isoforms (E2, E3, and E4) were determined from hepatic DNA by restriction isotyping (restriction enzyme isoform genotyping) of amplified apo E sequences. Pathologists graded the...

Topics

Adolescent
Adult
Aorta
Aorta, Thoracic
Aortic Diseases
Apolipoproteins E
Arteriosclerosis
Base Sequence
Black People
Cholesterol
Cholesterol, HDL

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Cholesterol, LDL

Cholesterol, VLDL

Coronary Artery Disease

Genotype

Humans

Male

Molecular Sequence Data

Source

Open in PubMed

Identifiers

PMID: 1680392
DOI: 10.1161/01.atv.11.5.1237

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1680392-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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