Article
Detection of angiotensin-converting enzyme gene insertion/deletion polymorphism from paraffin-embedded tissues: the Hisayama study.
Circulation journal : official journal of the Japanese Circulation Society - 1 Nov 2002
Arima Hisatomi, Kiyohara Yutaka, Tanizaki Yumihiro, Nakabeppu Yusaku, Kubo Michiaki, Kato Isao, Sueishi Katsuo, Tsuneyoshi Masazumi, Fujishima Masatoshi, Iida Mitsuo
Abstract excerpt
Previous studies have suggested that archival materials from formalin-fixed paraffin-embedded blocks are unsuitable for most molecular techniques because the extracted DNA can be severely degraded. Therefore, the present study was designed to investigate the accuracy of genotyping for the insertion (I)/deletion (D) polymorphism of the angiotensin-converting enzyme (ACE) gene from paraffin-embedded tissues of...
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