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Article

Polyamines are necessary for synthesis and stability of occludin protein in intestinal epithelial cells.

American journal of physiology. Gastrointestinal and liver physiology - 1 Jun 2005

Guo Xin, Rao Jaladanki N, Liu Lan, Zou Tongtong, Keledjian Kaspar M, Boneva Dessy, Marasa Bernard S, Wang Jian-Ying

Abstract excerpt

Occludin is an integral membrane protein that forms the sealing element of tight junctions and is critical for epithelial barrier function. Polyamines are implicated in multiple signaling pathways driving different biological functions of intestinal epithelial cells (IEC). The present study determined whether polyamines are involved in expression of occludin and play a role in intestinal epithelial barrier...

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Identifiers

PMID: 15691870
DOI: 10.1152/ajpgi.00407.2004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Polyamines are necessary for synthesis and stability of occludin protein in intestinal epithelial cells.PMID 15691870Read ↗

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