Article
Tumor necrosis factor-alpha gene promoter polymorphism is not associated with smoking-related COPD in Thailand.
Respirology (Carlton, Vic.) - 1 Jan 2005
Chierakul Nitipatana, Wongwisutikul Praphat, Vejbaesya Sasijit, Chotvilaiwan Kannikar
Abstract excerpt
OBJECTIVE: Susceptibility to COPD is, in part, genetically determined. Tumour necrosis factor (TNF)-alpha gene promoter polymorphisms have been investigated in different populations with inconsistent results. This study aimed to determine the genetic predisposition in Thai smoking-related COPD patients. METHODOLOGY: The polymorphism at position -308 of the TNF-alpha gene promoter was examined in 57 patients with...
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