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Association Between TNF-α-308, +489, −238 Polymorphism, and COPD Susceptibility: An Updated Meta-Analysis and Trial Sequential Analysis

21 Jan 2022

Abstract excerpt

The tumor necrosis factor alpha (TNF-α) polymorphism may play an important role in chronic obstructive pulmonary disease (COPD) susceptibility. However, the results are still inconclusive. Eligible studies were searched in Cochrane Library database, EMBASE, Pudmed, Web of science, China National Knowledge Infrastructure, and Wanfang database. Finally, a total of 27 case-control studies with 3473 COPD cases and...

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PMID: 35126452
DOI: 10.3389/fgene.2021.772032

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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