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Article

Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment.

Nutrition and cancer - 1 Nov 2011

Slattery Martha L, Lundgreen Abbie, Herrick Jennifer S, Caan Bette J, Potter John D, Wolff Roger K

Abstract excerpt

There is considerable biologic plausibility to the hypothesis that genetic variability in pathways involved in insulin signaling and energy homeostasis may modulate dietary risk associated with colorectal cancer. We utilized data from 2 population-based case-control studies of colon (n = 1,574 cases, 1,970 controls) and rectal (n = 791 cases, 999 controls) cancer to evaluate genetic variation in candidate SNPs...

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Source

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Identifiers

PMID: 21999454
DOI: 10.1080/01635581.2011.607545
PMCID: PMC3483090

Genes

PDK1
PTEN
PRKAG2
TSC1
TSC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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