Article
Different P105 promoter activities among natural variants of human papillomavirus type 18.
The Journal of infectious diseases - 1 Mar 2005
Sichero Laura, Franco Eduardo Luis, Villa Luisa Lina
Abstract excerpt
Association between non-European variants of human papillomavirus (HPV) type 16 (HPV-16) and HPV-18 and cervical lesions has been suggested. To compare the P105 promoter activity among 6 HPV-18 variants, their complete long control regions (LCRs), as well as that of HeLa cells, were cloned upstream of the luciferase gene and transiently transfected in C33 cells. Whereas the B18-2 European variant showed the...
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