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Article

Identification of a naturally occurring 21 bp deletion in alpha 2c noradrenergic receptor gene and cognitive correlates to antipsychotic treatment.

Pharmacological research - 1 Apr 2005

De Luca Vincenzo, Vincent John B, Müller Daniel J, Hwang Rudi, Shinkai Takahiro, Volavka Jan, Czobor Pal, Sheitman Brian B, Lindenmayer Jean-Pierre, Citrome Leslie, McEvoy Joseph P, Lieberman Jeffrey A, Kennedy James L

Abstract excerpt

Neurocognitive deficits are recognized as a cardinal feature of schizophrenia. Atypical antipsychotics have high affinity for many neurotransmitter receptors. Among these receptors, antipsychotics are antagonists of adrenoceptors, and this pharmacological property has been postulated to be involved in the mechanism of action of antipsychotics. We tested the hypotheses that clinical response and cognitive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Adrenergic, alpha-2

Share to Repetitive Sequences, Nucleic Acid

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Source

Identifiers

PMID: 15683753
DOI: 10.1016/j.phrs.2004.10.013

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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