Article
An investigation of the alpha1A-adrenergic receptor gene and antipsychotic-induced side-effects.
Human psychopharmacology - 1 Mar 2008
Saiz Pilar A, Susce Margaret T, Clark Dan A, Kerwin Robert W, Molero Patricio, Arranz Maria J, de Leon Jose
Abstract excerpt
Antipsychotic treatment is hampered by the induction of side-effects such as tardive dyskinesia (TD), weight gain, sedation and extrapyramidal side-effects (EPS). Identification of the factors related to their development would facilitate their avoidance and the improvement of antipsychotic treatment. It has been hypothesised that genetic variants in drug targeted receptors may contribute to the development of...
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