Article
No influence of adrenergic receptor polymorphisms on schizophrenia and antipsychotic response.
Neuroscience letters - 11 Feb 2000
Bolonna A A, Arranz M J, Munro J, Osborne S, Petouni M, Martinez M, Kerwin R W
Abstract excerpt
The adrenergic system plays an important role in psychiatric disorders such as depression and schizophrenia. Antagonism of the adrenergic receptor subtypes alpha1A and alpha2A has been found to have an antipsychotic effect. Genetic mutations in these receptors could be related to the alterations in the adrenergic system observed in psychiatric patients and to failure to respond to drug antagonism. We have studied...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
