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Article

A novel variant allele of OATP-C (SLCO1B1) found in a Japanese patient with pravastatin-induced myopathy.

Drug metabolism and pharmacokinetics - 1 Dec 2004

Morimoto Kaori, Oishi Tomoharu, Ueda Shiro, Ueda Madoka, Hosokawa Masakiyo, Chiba Kan

Abstract excerpt

We have recently found that the frequency of OATP-C*15 is significantly higher in patients who experienced myopathy after receiving pravastatin or atorvastatin than in patients without myopathy. However, there were two patients who experienced pravastatin-induced myopathy despite the fact that they did not possess OATP-C*15 or other known mutations of OATP-C that have been reported to decrease the function of...

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Identifiers

PMID: 15681900
DOI: 10.2133/dmpk.19.453

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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