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Article

Starter substrate specificities of wild-type and mutant polyketide synthases from Rutaceae.

Phytochemistry - 1 Feb 2005

Lukacin Richard, Schreiner Stephan, Silber Katrin, Matern Ulrich

Abstract excerpt

Chalcone synthases (CHSs) and acridone synthases (ACSs) belong to the superfamily of type III polyketide synthases (PKSs) and condense the starter substrate 4-coumaroyl-CoA or N-methylanthraniloyl-CoA with three malonyl-CoAs to produce flavonoids and acridone alkaloids, respectively. ACSs which have been cloned exclusively from Ruta graveolens share about 75-85% polypeptide sequence homology with CHSs from other...

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PMID: 15680984
DOI: 10.1016/j.phytochem.2004.11.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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