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Article

Notch3 and DeltaB maintain Müller glia quiescence and act as negative regulators of regeneration in the light‐damaged zebrafish retina

23 Sept 2020

Abstract excerpt

Damage to the zebrafish retina stimulates resident Müller glia to reprogram, reenter the cell cycle, divide asymmetrically, and produce neuronal progenitor cells that amplify and differentiate into the lost neurons. The transition from quiescent to proliferative Müller glia involves both positive and negative regulators. We previously demonstrated that the Notch signaling pathway represses retinal regeneration by...

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PMID: 32965734
DOI: 10.1002/glia.23912

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