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Article

Requirement of multiple basic helix-loop-helix genes for retinal neuronal subtype specification.

The Journal of biological chemistry - 2 Jul 2004

Akagi Tadamichi, Inoue Tomoyuki, Miyoshi Goichi, Bessho Yasumasa, Takahashi Masayo, Lee Jacqueline E, Guillemot François, Kageyama Ryoichiro

Abstract excerpt

Retinal precursor cells give rise to six types of neurons and one type of glial cell during development, and this process is controlled by multiple basic helix-loop-helix (bHLH) genes. However, the precise mechanism for specification of retinal neuronal subtypes, particularly horizontal neurons and photoreceptors, remains to be determined. Here, we examined retinas with three different combinations of triple bHLH...

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Identifiers

PMID: 15105417
DOI: 10.1074/jbc.M400871200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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