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Article

The pharmacological action of MT-7.

Life sciences - 18 Feb 2005

Onali Pierluigi, Adem Abdu, Karlsson Evert, Olianas Maria C

Abstract excerpt

The mamba toxin MT-7 is the most selective ligand currently available for the muscarinic M1 receptor subtype. The toxin binds stably to the receptor and blocks the agonist-induced activation non-competitively. Although its mode of action on M1 receptors is not yet fully understood, some of the toxin properties support an allosteric mechanism. Thus, the toxin fails to elicit a complete inhibition of the binding of...

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Identifiers

PMID: 15680165
DOI: 10.1016/j.lfs.2004.10.029

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NMS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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