Article
Association between IFNA genotype and the risk of systemic lupus erythematosus.
Clinical rheumatology - 1 Feb 2005
Nakashima Hitoshi, Matsuno Sawako, Akahoshi Mitsuteru, Miyake Katsuhisa, Inoue Yasushi, Tanaka Yosuke, Ninomiya Ichiro, Shimizu Sakiko, Igawa Takashi, Sadanaga Atsushi, Otsuka Takeshi, Harada Mine
Abstract excerpt
Systemic lupus erythematosus (SLE) is characterized by multisystem inflammation and production of autoantibodies, which can generate immune complexes and may cause tissue damage through the recognition of an autoantigen. Although many factors have been proposed, such as genetic factors, environmental factors, hormonal action, viruses, and dysregulation of cytokine production, the cause of this disease is not well...
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