Article
Genetic and hypoxic regulation of angiogenesis in gliomas.
Journal of neuro-oncology - 1 Nov 2004
Kaur Balveen, Tan Chalet, Brat Daniel J, Post Dawn E, Van Meir Erwin G
Abstract excerpt
Infiltrative astrocytic neoplasms are by far the most common malignant brain tumors in adults. Clinically, they are highly problematic due to their widely invasive nature which makes a complete resection almost impossible. Biologic progression of these tumors is inevitable and adjuvant therapies are only moderately effective in prolonging survival. Glioblastoma multiforme (GBM; WHO grade IV), the most malignant...
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