Article
Quorum sensing in Clostridium difficile: analysis of a luxS-type signalling system
26 Jan 2005
Abstract excerpt
The increasing incidence of Clostridium difficile-associated disease, and the problems associated with its control, highlight the need for additional countermeasures. The attenuation of virulence through the blockade of bacterial cell-to-cell communication (quorum sensing) is one potential therapeutic target. Preliminary studies have shown that C. difficile produces at least one potential signalling molecule....
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