Article
The <i>luxS</i> gene is involved in cell–cell signalling for toxin production in <i>Clostridium perfringens</i>
1 Apr 2002
Abstract excerpt
A Gram-positive anaerobic pathogen, Clostridium perfringens, causes clostridial myonecrosis or gas gangrene in humans by producing numerous extracellular toxins and enzymes that act in concert to degrade host tissues. C. perfringens possesses a homologue of the luxS gene that is reported to be responsible for the production of autoinducer 2 (AI-2), which participates in quorum sensing in bacteria. The luxS mutant...
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