Article
Production of shiga toxin by a luxS mutant of Escherichia coli O157:H7 in vivo and in vitro.
Microbiology and immunology - 1 Jan 2007
Jeon Byeonghwa, Itoh Kikuji
Abstract excerpt
Quorum sensing is a type of bacterial communication mediated by chemical signaling molecules called autoinducers (AIs). The production of AI-2 and AI-3 is dependent on the luxS gene in Escherichia coli O157:H7. A luxS mutation caused a minimal decrease (about 2-fold) in Shiga toxin (Stx) production in in vitro cultures using Luria-Bertani broth. The effect of a luxS mutation on the virulence of E. coli O157:H7...
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