Article
[A role of the PPAR gamma activation in insulin resistance].
Nihon rinsho. Japanese journal of clinical medicine - 1 Nov 2001
Yoshimasa Y
Abstract excerpt
PPAR gamma is a major determinants of adipocyte differentiation and its activation by ligands including thiazolidinedione(TZDs) and the endogenous ligands induces transcription of the genes involving glucose and lipid metabolism. By the experiments using animal models with obesity-related phenotypes and PPAR gamma knockout mouse and the results of genetics study regarding on the mutations and SNPs in human, it is...
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