Article
Influence of elastin gene polymorphism on the elastin content of the aorta: A study in 2 strains of rat.
Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 1999
Sauvage M, Osborne-Pellegrin M, Deslandes-Le Flohic F, Jacob M P
Abstract excerpt
The elastin content in the thoracic aorta of male Brown-Norway (BN) rats is 31.4+/-1.2% (dry weight), whereas that of male LOU rats is 37.2+/-1.0%. A similar difference in the elastin content of the thoracic aorta is also observed in female animals. Furthermore, in the thoracic aorta of young, growing rats as well as in cultured aortic smooth muscle cells, the steady-state level of elastin mRNA is significantly...
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