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Article

OASIS, a CREB/ATF-family member, modulates UPR signalling in astrocytes.

Nature cell biology - 1 Feb 2005

Kondo Shinichi, Murakami Tomohiko, Tatsumi Kouko, Ogata Maiko, Kanemoto Soshi, Otori Kumi, Iseki Ken, Wanaka Akio, Imaizumi Kazunori

Abstract excerpt

Endoplasmic reticulum (ER) stress transducers IRE1, PERK and ATF6 are well known to transduce signals from the ER to the cytoplasm and nucleus when unfolded proteins are accumulated in the ER. Here, we identified OASIS as a novel ER stress transducer. OASIS is a basic leucine zipper (bZIP) transcription factor of the CREB/ATF family with a transmembrane domain that allows it to associate with the ER. The molecule...

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Source

Identifiers

PMID: 15665855
DOI: 10.1038/ncb1213

Genes

ATF6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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