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Article

ATF family members as therapeutic targets in cancer: From mechanisms to pharmacological interventions

22 Aug 2024

Abstract excerpt

The activating transcription factor (ATF)/ cAMP-response element binding protein (CREB) family represents a large group of basic zone leucine zip (bZIP) transcription factors (TFs) with a variety of physiological functions, such as endoplasmic reticulum (ER) stress, amino acid stress, heat stress, oxidative stress, integrated stress response (ISR) and thus inducing cell survival or apoptosis. Interestingly, ATF...

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PMID: 39179052
DOI: 10.1016/j.phrs.2024.107355

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