Article
Cyclin E, p27 and mutant p53 do not predict the prognosis in AJCC stage II colorectal carcinomas.
The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi - 1 Dec 2004
Lim Yun Jeong, Kim Young-Ho, Ahn Geung Hwan, Chun Ho Kwung, Jang Woo Young, Lee Jun Haeng, Son Hee Jung, Rhee Poong-Lyul, Kim Jae J, Paik Seung Woon, Yoo Byung Chul, Rhee Jong Chul
Abstract excerpt
BACKGROUND/AIMS: Carcinogenesis is characterized by the abnormal regulation of cell cycle. The abnormal expression of the regulators of cell cycle may be related to the prognosis. Since the clinical significance of the expression of the three proteins in colorectal carcinomas is still controversial, we evaluated the prognostic value of the expression of cyclin E, p27 and mutant p53 in stage II colorectal cancer....
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