Article
Inactivation of the cysteine protease SpeB affects hyaluronic acid capsule expression in group A streptococci.
Microbial pathogenesis - 1 Apr 2000
Woischnik M, Buttaro B A, Podbielski A
Abstract excerpt
The human pathogen Streptococcus pyogenes expresses several virulence factors that are required for the pathogens survival within the host and the concomitant development of disease. To examine the influence of one virulence factor, the extracellular cysteine protease SpeB, on the expression of other virulence factors, the speB structural gene of a serotype M3 and M49 strain was inactivated. Morphologic...
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