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Article

Detection of a hidden folding intermediate of the third domain of PDZ.

Journal of molecular biology - 11 Feb 2005

Feng Hanqiao, Vu Ngoc-Diep, Bai Yawen

Abstract excerpt

The folding pathway of the third domain of PDZ from the synaptic protein PSD-95 was characterized using kinetic and equilibrium methods by monitoring the fluorescence signal from a Trp residue that is incorporated at a near-surface position. Kinetic folding of this domain showed multiple exponential phases, whereas unfolding showed a single exponential phase. The slow kinetic phases were attributed to...

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Source

Identifiers

PMID: 15663949
DOI: 10.1016/j.jmb.2004.11.040

Genes

PSD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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