Article
Induction of class II major histocompatibility antigens on thyroid, adult pancreatic islet, and fetal proislet allografts.
Transplantation - 1 Apr 1992
Warren H S, Hodder M J, Allan W, Hume D A, Simeonovic C J
Abstract excerpt
Cultured BALB/c (H-2d) thyroid, adult pancreatic islet and fetal proislet tissues can be accepted permanently in CBA/H (H-2k) recipients until rejection is triggered by the transfer of antidonor strain activated immune T cells. Class II MHC antigens are not expressed on the accepted grafts and are induced following immune cell transfer, but expression is quantitatively and qualitatively different for the...
Topics
- Animals
- Fetus
- Graft Rejection
- Histocompatibility Antigens Class II
- Interferon-gamma
- Islets of Langerhans
- Islets of Langerhans Transplantation
- Male
- Mice
- Mice, Inbred Strains
- Phenotype