Article
Induction of embryonic major histocompatibility complex antigen expression by gamma-IFN.
Journal of reproductive immunology - 1 Jul 1993
Warner C M, Almquist C D, Toulimat M H, Xu Y
Abstract excerpt
Preimplantation mouse embryos were incubated in vitro with mouse recombinant gamma-interferon (IFN). The effect of the gamma-IFN on major histocompatibility complex (MHC) class I antigen expression was tested using an ELISA procedure. It was found that there is a doubling of Db antigens and a tri...
Topics
- Animals
- Blastocyst
- Cell Division
- Embryonic and Fetal Development
- Female
- Gene Expression Regulation
- Genes, MHC Class I
- H-2 Antigens
- Histocompatibility Antigens Class I
- Interferon-gamma
- Mice
- Mice, Inbred C57BL
- Phenotype
- Recombinant Proteins