Article
RNAi as a tool to study cell biology: building the genome-phenome bridge.
Current opinion in cell biology - 1 Feb 2005
Gunsalus Kristin C, Piano Fabio
Abstract excerpt
In the few short years since its discovery, RNA interference (RNAi) has revolutionized the functional analysis of genomes: both technical and conceptual approaches to the investigation of gene function are being transformed as a result of this new technology. Genome-scale RNAi analyses have already been performed in the model organisms Caenorhabditis elegans (in vivo) and Drosophila melanogaster (in cell lines),...
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