Article
Multiple 5'-splice variants of the rat glutamate transporter-1.
Brain research. Molecular brain research - 5 Jan 2005
Rozyczka Joanna, Engele Jürgen
Abstract excerpt
In most brain areas, uptake of extracellular glutamate predominantly occurs through the glutamate transporter subtype, glutamate transporter-1 (GLT-1), which is enriched in astroglia. Here, we report the identification of five splice variants of the 5'-leader sequence of rat GLT-1 which contain varying numbers of upstream open reading frames and encode putative GLT-1 proteins with two distinct N-terminal...
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