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Article

Inherited disorders of IL-12- and IFNgamma-mediated immunity: a molecular genetics update.

Molecular immunology - 1 May 2002

Döffinger R, Dupuis S, Picard C, Fieschi C, Feinberg J, Barcenas-Morales G, Casanova J-L

Abstract excerpt

In the last 6 years, considerable advances have been made in the molecular analysis of a rare clinical syndrome: Mendelian susceptibility to mycobacterial disease (MSMD). Infection with poorly virulent environmental non-tuberculous mycobacteria (NTM) or vaccination with bacillus Calmette-Guerin (BCG) may cause disseminating and even fatal disease in individuals suffering from this syndrome. Mutations in five...

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Source

Identifiers

PMID: 12009568
DOI: 10.1016/s0161-5890(02)00017-2

Genes

IFNGR1
IFNGR2
NTM
STAT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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