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Article

Impaired interferon gamma-mediated immunity and susceptibility to mycobacterial infection in childhood.

Pediatric research - 1 Jul 2001

Remus N, Reichenbach J, Picard C, Rietschel C, Wood P, Lammas D, Kumararatne D S, Casanova J L

Abstract excerpt

Mendelian susceptibility to poorly virulent mycobacteria such as bacillus Calmette-Guerin (BCG) and environmental nontuberculous mycobacteria is a clinically heterogeneous syndrome. The clinical features of affected children cover a continuous spectrum from disseminated lethal bacillus Calmette-Guerin infection to local recurrent nontuberculous mycobacterial infection. Different types of mutations in four genes...

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Source

Identifiers

PMID: 11420412
DOI: 10.1203/00006450-200107000-00005

Genes

IFNGR1
IFNGR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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