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Article

Back-priming mode of phi6 RNA-dependent RNA polymerase.

The Journal of general virology - 1 Feb 2005

Laurila Minni R L, Salgado Paula S, Stuart David I, Grimes Jonathan M, Bamford Dennis H

Abstract excerpt

The RNA-dependent RNA polymerase of the double-stranded RNA bacteriophage phi6 is capable of primer-independent initiation, as are many RNA polymerases. The structure of this polymerase revealed an initiation platform, composed of a loop in the C-terminal domain (QYKW, aa 629-632), that was essential for de novo initiation. A similar element has been identified in hepatitis C virus RNA-dependent RNA polymerase....

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PMID: 15659773
DOI: 10.1099/vir.0.80492-0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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