Formation of a functional hepatitis B virus replication initiation complex involves a major structural alteration in the RNA template.

doi:10.1128/MCB.18.11.6265

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Article

Formation of a functional hepatitis B virus replication initiation complex involves a major structural alteration in the RNA template.

Molecular and cellular biology - 1 Nov 1998

Beck J, Nassal M

Abstract excerpt

The DNA genome of a hepatitis B virus is generated by reverse transcription of the RNA pregenome. Replication initiation does not involve a nucleic acid primer; instead, the hepadnavirus P protein binds to the structured RNA encapsidation signal epsilon, from which it copies a short DNA primer th...

Topics

Base Sequence
DNA Replication
Gene Products, pol
Hepatitis B Virus, Duck
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
RNA, Viral
RNA-Binding Proteins
RNA-Directed DNA Polymerase
Ribonucleoproteins
Viral Proteins

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