Article
A complex mechanism determines polarity of DNA replication fork arrest by the replication terminator complex of Bacillus subtilis.
The Journal of biological chemistry - 1 Apr 2005
Duggin Iain G, Matthews Jacqueline M, Dixon Nicholas E, Wake R Gerry, Mackay Joel P
Abstract excerpt
Two dimers of the replication terminator protein (RTP) of Bacillus subtilis bind to a chromosomal DNA terminator site to effect polar replication fork arrest. Cooperative binding of the dimers to overlapping half-sites within the terminator is essential for arrest. It was suggested previously that polarity of fork arrest is the result of the RTP dimer at the blocking (proximal) side within the complex binding...
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