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Article

A critical role of the 3' terminus of nascent DNA chains in recognition of stalled replication forks.

The Journal of biological chemistry - 24 Oct 2003

Mizukoshi Toshimi, Tanaka Taku, Arai Ken-ichi, Kohda Daisuke, Masai Hisao

Abstract excerpt

Arrest of replication forks by various internal and external threats evokes a myriad of cellular reactions, collectively known as DNA replication checkpoint responses. In bacteria, PriA is essential for restoration of stalled replication forks and recombinational repair of double-stranded DNA breaks and is a candidate sensor protein that may recognize arrested forks. Here, we report that PriA protein specifically...

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Identifiers

PMID: 12917421
DOI: 10.1074/jbc.C300285200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A critical role of the 3' terminus of nascent DNA chains in recognition of stalled replication forks.PMID 12917421Read ↗

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PriA-directed replication fork restart in Escherichia coli.Semantic proximity Read ↗

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The DNA replication priming protein, PriA, is required for homologous recombination and double-strand break repair.Semantic proximity Read ↗

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