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Article

MEIS C termini harbor transcriptional activation domains that respond to cell signaling.

The Journal of biological chemistry - 18 Mar 2005

Huang He, Rastegar Mojgan, Bodner Caroline, Goh Siew-Lee, Rambaldi Isabel, Featherstone Mark

Abstract excerpt

MEIS proteins form heteromeric DNA-binding complexes with PBX monomers and PBX.HOX heterodimers. We have shown previously that transcriptional activation by PBX.HOX is augmented by either protein kinase A (PKA) or the histone deacetylase inhibitor trichostatin A (TSA). To examine the contribution of MEIS proteins to this response, we used the chromatin immunoprecipitation assay to show that MEIS1 in addition to...

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Source

Identifiers

PMID: 15654074
DOI: 10.1074/jbc.M413963200

Genes

MEIS1
HOXA1
HOXB1
PBX1
PREP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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