Article
Expression of MXI1, a Myc antagonist, is regulated by Sp1 and AP2.
The Journal of biological chemistry - 1 Oct 1999
Benson L Q, Coon M R, Krueger L M, Han G C, Sarnaik A A, Wechsler D S
Abstract excerpt
MXI1, a member of the MAD family of Myc antagonists, encodes a transcription factor whose expression must be tightly regulated to maintain normal cell growth and differentiation. To more closely investigate the transcriptional regulation of the human MXI1 gene, we have cloned and characterized the MXI1 promoter. After clarification of the 5'- and 3'-untranslated regions of the cDNA (indicating that the true...
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