Article
Absence of nucleotide polymorphism in a Plasmodium vivax multidrug resistance gene after failure of mefloquine prophylaxis in French Guyana.
Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Mar 2005
Picot S, Brega S, Gérôme P, Velut G, de Monbrison F, Cheminel V, Peyron F
Abstract excerpt
Vivax malaria is widespread and resistance has been described for chloroquine and sulfadoxine-pyrimethamine. We report on evidence of failure of mefloquine prophylaxis in a French soldier who contracted Plasmodium vivax in French Guyana, South America. Despite regular weekly mefloquine prophylaxis (250 mg/d), the patient presented with a first episode of vivax malaria, which was treated by chloroquine alone, then...
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