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Article

Different SNPs in Fasciola hepatica P-glycoprotein from diverse Latin American populations are not associated with Triclabendazole resistance.

Molecular and biochemical parasitology - 1 Sept 2018

Solana María Victoria, Domínguez María Fernanda, Scarcella Silvana, Radio Santiago, Smircich Pablo, Fernández Silvina, Solana Hugo, Tort José F

Abstract excerpt

The use of Triclabendazole for controlling fasciolosis is compromised by increased drug resistance affecting livestock and humans. Although the mode of action of TCBZ is still unknown, putative candidates and markers of resistance have been advanced. A single nucleotide polymorphism (T687 G) in F. hepatica PGP was proposed as marker of resistance in a small scale study of European susceptible and resistant...

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Identifiers

PMID: 30055185
DOI: 10.1016/j.molbiopara.2018.07.005

Genes

PGP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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