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Article

Absence of correlation between ex vivo susceptibility to doxycycline and pfteQ-pfmdt gene polymorphism in French Guiana.

Malaria journal - 25 Jul 2015

Mura Marie, Briolant Sébastien, Donato Damien, Volney Béatrice, Pelleau Stéphane, Musset Lise, Legrand Eric

Abstract excerpt

BACKGROUND: In French Guiana, doxycycline is used for both chemoprophylaxis and the treatment of malaria. The presence of isolates with reduced ex vivo susceptibility to doxycycline in French Guiana makes it critical to identify any genetic determinants contributing to the chemosusceptibility level of Plasmodium falciparum to doxycycline, such as pfmdt and pftetQ, which were recently identified as potential...

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Identifiers

PMID: 26206143
DOI: 10.1186/s12936-015-0788-y
PMCID: PMC4513625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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